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If you regularly drink diet soda and use artificial sweeteners because you think it will help you lose weight, you're unwittingly sabotaging your efforts. Sure, artificial sweeteners like sucralose, saccharine, and aspartame save on calories, but a recent Israeli study shows they can skew the composition of gut bacteria, or our  microbiome   in a way that promotes obesity and diabetes.

We're increasingly learning about the trillions of bacteria that live in the gut, weighing in at 3 to 4 pounds, and the profound influence they have on human health and behavior. In addition to providing nutrients and aiding in the digestive process, gut bacteria also influence moods, behavior and mental health; immune function; energy levels; and how well we burn or store fat.

Our microbiome consists of beneficial and harmful bacteria. We carry a diverse array of bacteria — hundreds of varieties — and the proportions of these bacteria can play a role in how our body, brain, and even personality function.

Unfortunately, as promising as the idea of calorie-free drinks sound, they skew the balance of bacteria in the gut toward high blood sugar. This in turn promotes insulin resistance (pre-diabetes), fat storage, and chronic inflammation. In the study this phenomenon was referred to as glucose intolerance.

Artificial sweeteners promote high blood sugar

The  study  began by looking at groups of mice that were given plain water, water with sugar added, or water with an artificial sweetener added. After 10 weeks the groups given the artificial sweeteners consistently showed high blood sugar, regardless of whether the sweetener used was saccharine, aspartame, or sucralose. Even a group of mice given a high-fat diet and sugar water maintained healthy blood glucose levels while the group given a high-fat diet and artificial sweeteners did not.

To further validate the findings, researchers transplanted fecal matter from the mice given artificial sweeteners into germ-free mice. The germ-free, too, developed glucose intolerance. When scientists gave the affected mice antibiotics to kill the overgrowth of fat-promoting bacteria, their blood sugar normalized.

Studying artificial sweeteners in humans

Of course, not everyone is going to be sold on the results of a study using mice. After all, we're not mice. So the researchers ran the study on a small group of  human  volunteers, all of whom showed elevated blood sugar and alterations in their gut bacteria composition after just one week.

How to cultivate healthy gut bacteria

In addition to avoiding artificial sweeteners, there are other ways to cultivate your inner garden of gut flora to promote fat burning instead of weight gain. One of the best ways is to make  vegetables  the primary part of your diet, including cultured vegetables. Not only are they loaded with fiber, vitamins, and minerals, they promote and maintain good gut bacteria. At the same time, avoiding processed foods, sugars and sweeteners, and artificial additives will prevent the bad bacteria from taking over and giving you health problems.

Ask my office for probiotic supplement recommendations to further enhance your good gut bacteria.