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Are Pyrolurea and Lyme disease connected?

Pyroluria is a genetic condition in which the body produces excess kryptopyrrole (KP), a waste product of hemoglobin synthesis. The excess KP binds to vitamin B6 and zinc, leading to deficiencies of these important nutrients. This condition is linked to a number of health problems, including anxiety, depression, and schizophrenia. In recent years, researchers have also investigated a possible link between pyroluria and Lyme disease.

Lyme disease is a tick-borne illness caused by the bacterium Borrelia burgdorferi. The disease can cause a wide range of symptoms, including fever, headache, joint pain, and fatigue. In some cases, the disease can cause chronic symptoms that persist even after treatment. Researchers have found that people with Lyme disease often have low levels of zinc and vitamin B6, which are both essential for immune function and maintaining healthy nervous system function.

Pyroluria can cause deficiencies of both zinc and vitamin B6, leading to immune dysfunction and nervous system problems. These problems could make people with pyroluria more susceptible to Lyme disease and other tick-borne illnesses. Some studies have found that people with pyroluria are more likely to have a positive test for Lyme disease and experience more severe symptoms of the disease.

In addition, some researchers have proposed that Lyme disease could trigger pyroluria. They suggest that the infection could lead to an increase in KP production, leading to a greater depletion of zinc and vitamin B6. This could cause the symptoms of Lyme disease to become more severe and persist longer than in people without pyroluria.

While the link between pyroluria and Lyme disease is still being studied, it is clear that people with Lyme disease should be tested for pyroluria and treated if necessary. Treatment for pyroluria typically involves supplementing with zinc and vitamin B6, along with other nutritional supplements. By correcting the nutrient deficiencies associated with pyroluria, people with Lyme disease may be able to recover more quickly and avoid chronic symptoms.

In conclusion, there appears to be a connection between pyroluria and Lyme disease. Pyroluria can cause deficiencies of zinc and vitamin B6, which are important for immune function and nervous system health. These deficiencies could make people with pyroluria more susceptible to Lyme disease and other tick-borne illnesses. Additionally, some researchers have suggested that Lyme disease could trigger pyroluria, leading to more severe symptoms and a longer recovery time. People with Lyme disease should be tested for pyroluria and treated if necessary to help support their immune system and overall health.

Meet the Author

Dr. Matz DC

Dr. Jeffrey E. Matz, DC, MS, is a Board Certified Chiropractic Physician. He is licensed to practice in SC, NC, and GA. Dr. Matz is passionate about functional medicine and strives to help patients achieve optimal health. His focus is on helping our members with hormone imbalances, autoimmune conditions, chronic pain conditions, and diabetes. Among the thousands of people Dr. Matz has treated include Carolina Panthers football players, PGA Tour and Champions Tour golfers, collegiate athletes, and local and international celebrities. Dr. Matz was a semiprofessional cyclist, and has competed in triathlons for the last 7 years, including completing an IRONMAN triathlon.

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